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PDBsum entry 3vpg

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protein ligands Protein-protein interface(s) links
Oxidoreductase PDB id
3vpg
Jmol
Contents
Protein chains
310 a.a.
Ligands
GOL ×2
Waters ×795
PDB id:
3vpg
Name: Oxidoreductase
Title: L-lactate dehydrogenase from thermus caldophilus gk24
Structure: L-lactate dehydrogenase. Chain: a, b, c, d. Synonym: l-ldh. Engineered: yes
Source: Thermus caldophilus. Organism_taxid: 272. Gene: ldh. Expressed in: escherichia coli. Expression_system_taxid: 562
Resolution:
1.80Å     R-factor:   0.191     R-free:   0.227
Authors: K.Arai,T.Ohno,A.Miyanaga,S.Fushinobu,H.Taguchi
Key ref: K.Arai et al. Crystal structure of active and inactive l-Lactate dehydrogenase from thermophile bacteria thermus caldo gk24. To be published, .
Date:
01-Mar-12     Release date:   06-Mar-13    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P06150  (LDH_THECA) -  L-lactate dehydrogenase
Seq:
Struc:
310 a.a.
310 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.1.1.1.27  - L-lactate dehydrogenase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: (S)-lactate + NAD+ = pyruvate + NADH
(S)-lactate
Bound ligand (Het Group name = GOL)
matches with 71.43% similarity
+ NAD(+)
= pyruvate
+ NADH
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   1 term 
  Biological process     oxidation-reduction process   4 terms 
  Biochemical function     catalytic activity     4 terms