spacer
spacer

PDBsum entry 3vku

Go to PDB code: 
protein ligands Protein-protein interface(s) links
Oxidoreductase PDB id
3vku
Jmol
Contents
Protein chains
290 a.a.
311 a.a.
Ligands
SO4 ×12
Waters ×631
PDB id:
3vku
Name: Oxidoreductase
Title: Penta mutant of lactobacillus casei lactate dehydrogenase
Structure: L-lactate dehydrogenase. Chain: a, b, c, d, e, f. Synonym: l-ldh. Engineered: yes. Mutation: yes
Source: Lactobacillus casei. Organism_taxid: 1582. Gene: ldh. Expressed in: escherichia coli. Expression_system_taxid: 562
Resolution:
1.96Å     R-factor:   0.209     R-free:   0.260
Authors: K.Arai,A.Miyanaga,H.Uchikoba,S.Fushinobu,H.Taguchi
Key ref: K.Arai et al. Crystal structure of penta mutant of l-Lactate dehydr from lactobacillus casei. To be published, .
Date:
22-Nov-11     Release date:   28-Nov-12    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P00343  (LDH_LACCA) -  L-lactate dehydrogenase
Seq:
Struc:
326 a.a.
290 a.a.*
Protein chains
Pfam   ArchSchema ?
P00343  (LDH_LACCA) -  L-lactate dehydrogenase
Seq:
Struc:
326 a.a.
311 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 10 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: Chains A, B, C, D, E, F: E.C.1.1.1.27  - L-lactate dehydrogenase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: (S)-lactate + NAD+ = pyruvate + NADH
(S)-lactate
+ NAD(+)
= pyruvate
+ NADH
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   1 term 
  Biological process     oxidation-reduction process   4 terms 
  Biochemical function     catalytic activity     4 terms