PDBsum entry 3vjs

Transcription

PDB id: 3vjs

Contents

Protein chain

239 a.a.

Ligands

ASN-HIS-PRO-MET-LEU-MET-ASN-LEU-LEU-LYS

10S

Waters ×66

PDB id:

3vjs

Name:

Transcription

Title:

Vitamin d receptor complex with a carborane compound

Structure:

Vitamin d3 receptor. Chain: a. Fragment: ligand-binding domain, unp residues 116-423. Synonym: vdr, 1,25-dihydroxyvitamin d3 receptor, nuclear receptor subfamily 1 group i member 1. Engineered: yes. Mutation: yes. Peptide from mediator of RNA polymerase ii transcription subunit 1.

Source:

Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: vdr, nr1i1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Homo sapiens. Human.

Resolution:

1.93Å R-factor: 0.232 R-free: 0.282

Authors:

S.Fujii,M.Masuno,H.Kagechika,M.Nakabayashi,N.Ito

Key ref:

S.Fujii et al. (2011). Boron cluster-based development of potent nonsecosteroidal vitamin D receptor ligands: direct observation of hydrophobic interaction between protein surface and carborane. J Am Chem Soc, 133, 20933-20941. PubMed id: 22066785

Date:

31-Oct-11 Release date: 08-Feb-12

Protein chain

P13053  (VDR_RAT) -  Vitamin D3 receptor from Rattus norvegicus

Seq: 423 a.a.

Struc: 239 a.a.

J Am Chem Soc 133:20933-20941 (2011)

PubMed id: 22066785

Boron cluster-based development of potent nonsecosteroidal vitamin D receptor ligands: direct observation of hydrophobic interaction between protein surface and carborane.

S.Fujii, H.Masuno, Y.Taoda, A.Kano, A.Wongmayura, M.Nakabayashi, N.Ito, M.Shimizu, E.Kawachi, T.Hirano, Y.Endo, A.Tanatani, H.Kagechika.

ABSTRACT

No abstract given.