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PDBsum entry 3v0f

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protein ligands Protein-protein interface(s) links
Hydrolase PDB id
3v0f
Jmol
Contents
Protein chains
331 a.a.
Ligands
PO4 ×2
Waters ×873
PDB id:
3v0f
Name: Hydrolase
Title: Crystal structure of ciona intestinalis voltage sensor-conta phosphatase (ci-vsp), residues 241-576(c363s), form ii
Structure: Voltage-sensor containing phosphatase. Chain: a, b. Fragment: unp residues 241-576. Engineered: yes. Mutation: yes
Source: Ciona intestinalis. Transparent sea squirt. Organism_taxid: 7719. Gene: ci-vsp. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.30Å     R-factor:   0.142     R-free:   0.175
Authors: L.Liu,S.C.Kohout,Q.Xu,S.Muller,C.Kimberlin,E.Y.Isacoff,D.L M
Key ref: L.Liu et al. (2012). A glutamate switch controls voltage-sensitive phosphatase function. Nat Struct Mol Biol, 19, 633-641. PubMed id: 22562138
Date:
07-Dec-11     Release date:   09-May-12    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q4W8A1  (Q4W8A1_CIOIN) -  Voltage-sensor containing phosphatase
Seq:
Struc:
 
Seq:
Struc:
576 a.a.
331 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 3 residue positions (black crosses)

 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     protein dephosphorylation   1 term 
  Biochemical function     protein tyrosine/serine/threonine phosphatase activity     1 term  

 

 
Nat Struct Mol Biol 19:633-641 (2012)
PubMed id: 22562138  
 
 
A glutamate switch controls voltage-sensitive phosphatase function.
L.Liu, S.C.Kohout, Q.Xu, S.Müller, C.R.Kimberlin, E.Y.Isacoff, D.L.Minor.
 
  ABSTRACT  
 
No abstract given.