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PDBsum entry 3ui4

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protein ligands metals links
Isomerase PDB id
3ui4
Jmol
Contents
Protein chain
101 a.a.
Ligands
SO4 ×4
Metals
_CL ×2
Waters ×239
PDB id:
3ui4
Name: Isomerase
Title: 0.8 a resolution crystal structure of human parvulin 14
Structure: Peptidyl-prolyl cis-trans isomerase nima-interact chain: a. Synonym: parvulin-14, par14, hpar14, parvulin-17, par17, hp peptidyl-prolyl cis-trans isomerase pin4, ppiase pin4, pept prolyl cis/trans isomerase epvh, hepvh, rotamase pin4. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pin4, q9y237. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Resolution:
0.80Å     R-factor:   0.095     R-free:   0.098
Authors: J.W.Mueller,N.M.Link,A.Matena,L.Hoppstock,A.Rueppel,P.Bayer, W.Blankenfeldt
Key ref: J.W.Mueller et al. (2011). Crystallographic proof for an extended hydrogen-bonding network in small prolyl isomerases. J Am Chem Soc, 133, 20096-20099. PubMed id: 22081960
Date:
04-Nov-11     Release date:   07-Dec-11    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q9Y237  (PIN4_HUMAN) -  Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4
Seq:
Struc:
131 a.a.
101 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 2 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.5.2.1.8  - Peptidylprolyl isomerase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Peptidylproline (omega=180) = peptidylproline (omega=0)
Peptidylproline (omega=180)
= peptidylproline (omega=0)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biochemical function     isomerase activity     1 term  

 

 
    Added reference    
 
 
J Am Chem Soc 133:20096-20099 (2011)
PubMed id: 22081960  
 
 
Crystallographic proof for an extended hydrogen-bonding network in small prolyl isomerases.
J.W.Mueller, N.M.Link, A.Matena, L.Hoppstock, A.Rüppel, P.Bayer, W.Blankenfeldt.
 
  ABSTRACT  
 
No abstract given.