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PDBsum entry 3tzh

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protein ligands Protein-protein interface(s) links
Oxidoreductase PDB id
3tzh
Jmol
Contents
Protein chains
(+ 0 more) 247 a.a.
Ligands
UNX ×47
SO4 ×19
GOL ×7
Waters ×868
PDB id:
3tzh
Name: Oxidoreductase
Title: Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reduc (fabg)(f187a) from vibrio cholerae
Structure: 3-oxoacyl-[acyl-carrier protein] reductase. Chain: a, b, c, d, e, f. Engineered: yes. Mutation: yes
Source: Vibrio cholerae. Organism_taxid: 593588. Strain: mj-1236. Gene: vc2021, vcd_002346. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.10Å     R-factor:   0.159     R-free:   0.191
Authors: J.Hou,M.Chruszcz,H.Zheng,D.R.Cooper,T.Osinski,I.Shumilin, W.F.Anderson,W.Minor,Center For Structural Genomics Of Infe Diseases (Csgid)
Date:
27-Sep-11     Release date:   19-Oct-11    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
C3NP04  (C3NP04_VIBCJ) -  3-oxoacyl-[acyl-carrier protein] reductase
Seq:
Struc:
248 a.a.
247 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Enzyme reactions 
   Enzyme class: E.C.1.1.1.100  - 3-oxoacyl-[acyl-carrier-protein] reductase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: (3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP+ = 3-oxoacyl-[acyl- carrier-protein] + NADPH
(3R)-3-hydroxyacyl-[acyl-carrier-protein]
Bound ligand (Het Group name = GOL)
matches with 55.56% similarity
+ NADP(+)
= 3-oxoacyl-[acyl- carrier-protein]
+ NADPH
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     metabolic process   3 terms 
  Biochemical function     nucleotide binding     4 terms