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PDBsum entry 3tl2

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protein ligands links
Oxidoreductase PDB id
3tl2
Jmol
Contents
Protein chain
312 a.a.
Ligands
EDO ×2
SCN ×2
Waters ×413
PDB id:
3tl2
Name: Oxidoreductase
Title: Crystal structure of bacillus anthracis str. Ames malate deh in closed conformation.
Structure: Malate dehydrogenase. Chain: a. Engineered: yes
Source: Bacillus anthracis. Anthrax,anthrax bacterium. Organism_taxid: 1392. Strain: ames. Gene: bas4486, ba_4837, gbaa_4837, mdh. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Resolution:
1.70Å     R-factor:   0.159     R-free:   0.198
Authors: B.J.Blus,M.Chruszcz,K.L.Tkaczuk,T.Osinski,M.Cymborowski,M.Ku S.Grimshaw,A.Savchenko,W.F.Anderson,W.Minor,Center For Stru Genomics Of Infectious Diseases (Csgid)
Key ref: B.J.Blus et al. Crystal structure of bacillus anthracis str. Ames mal dehydrogenase in closed conformation.. To be published, .
Date:
29-Aug-11     Release date:   21-Sep-11    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q6HSF4  (MDH_BACAN) -  Malate dehydrogenase
Seq:
Struc:
312 a.a.
312 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.1.1.1.37  - Malate dehydrogenase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
Citric acid cycle
      Reaction: (S)-malate + NAD+ = oxaloacetate + NADH
(S)-malate
Bound ligand (Het Group name = EDO)
matches with 44.44% similarity
+ NAD(+)
= oxaloacetate
+ NADH
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     oxidation-reduction process   5 terms 
  Biochemical function     catalytic activity     4 terms