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PDBsum entry 3sil

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protein ligands metals links
Glycosidase PDB id
3sil
Jmol
Contents
Protein chain
379 a.a. *
Ligands
PO4
GOL ×6
Metals
__K
Waters ×561
* Residue conservation analysis
PDB id:
3sil
Name: Glycosidase
Title: Sialidase from salmonella typhimurium
Structure: Sialidase. Chain: a. Engineered: yes. Mutation: yes
Source: Salmonella typhimurium. Organism_taxid: 99287. Strain: lt2. Variant: ta263, prototroph. Gene: nanh. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.05Å     R-factor:   0.116     R-free:   0.147
Authors: E.F.Garman,G.M.Sheldrick
Key ref: E.F.Garman et al. An enzyme at atomic resolution: the 1.05 a structure of salmonella typhimurium neuraminidase (sialidase). To be published, .
Date:
07-Jul-98     Release date:   11-Nov-98    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P29768  (NANH_SALTY) -  Sialidase
Seq:
Struc:
382 a.a.
379 a.a.
Key:    PfamA domain  PfamB domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.3.2.1.18  - Exo-alpha-sialidase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     metabolic process   2 terms 
  Biochemical function     exo-alpha-(2->3)-sialidase activity     6 terms