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PDBsum entry 3s3b

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protein ligands metals Protein-protein interface(s) links
Oxidoreductase PDB id
3s3b
Jmol
Contents
Protein chains
555 a.a.
166 a.a.
33 a.a.
Ligands
HEM
HAS
CUA
Metals
_XE ×3
_CU
PDB id:
3s3b
Name: Oxidoreductase
Title: Structure of thermus thermophilus cytochrome ba3 oxidase 240 depressurization
Structure: CytochromE C oxidase subunit 1. Chain: a. Synonym: cytochromE C ba(3) subunit i, cytochromE C oxidase polypeptide i, cytochrome cba3 subunit 1. Engineered: yes. CytochromE C oxidase subunit 2. Chain: b. Synonym: cytochromE C ba(3) subunit ii, cytochromE C oxidas polypeptide ii, cytochrome cba3 subunit 2.
Source: Thermus thermophilus. Organism_taxid: 300852. Strain: hb8. Gene: cbaa. Expressed in: thermus thermophilus. Expression_system_taxid: 300852. Gene: cbab, cbac. Gene: cbad.
Resolution:
3.30Å     R-factor:   0.259     R-free:   0.299
Authors: V.M.Luna,J.A.Fee,A.A.Deniz,C.D.Stout
Key ref: V.M.Luna et al. (2012). Mobility of Xe atoms within the oxygen diffusion channel of cytochrome ba(3) oxidase. Biochemistry, 51, 4669-4676. PubMed id: 22607023 DOI: 10.1021/bi3003988
Date:
18-May-11     Release date:   23-May-12    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q5SJ79  (COX1_THET8) -  Cytochrome c oxidase subunit 1
Seq:
Struc:
 
Seq:
Struc:
562 a.a.
555 a.a.
Protein chain
Pfam   ArchSchema ?
Q5SJ80  (COX2_THET8) -  Cytochrome c oxidase subunit 2
Seq:
Struc:
168 a.a.
166 a.a.
Protein chain
Pfam   ArchSchema ?
P82543  (COXA_THET8) -  Cytochrome c oxidase polypeptide 2A
Seq:
Struc:
34 a.a.
33 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: Chains A, B, C: E.C.1.9.3.1  - Cytochrome-c oxidase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O
4 × ferrocytochrome c
Bound ligand (Het Group name = HEM)
matches with 63.64% similarity
+ O(2)
+ 4 × H(+)
= 4 × ferricytochrome c
+ 2 × H(2)O
      Cofactor: Cu cation
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     membrane   4 terms 
  Biological process     oxidation-reduction process   7 terms 
  Biochemical function     electron carrier activity     7 terms  

 

 
    reference    
 
 
DOI no: 10.1021/bi3003988 Biochemistry 51:4669-4676 (2012)
PubMed id: 22607023  
 
 
Mobility of Xe atoms within the oxygen diffusion channel of cytochrome ba(3) oxidase.
V.M.Luna, J.A.Fee, A.A.Deniz, C.D.Stout.
 
  ABSTRACT  
 
No abstract given.