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PDBsum entry 3rid

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protein ligands Protein-protein interface(s) links
Hydrolase PDB id
3rid
Jmol
Contents
Protein chains
124 a.a.
Ligands
CGP ×4
PO4 ×4
Waters ×546
PDB id:
3rid
Name: Hydrolase
Title: X-ray structure of thE C-terminal swapped dimer of p114a var ribonuclease a
Structure: Ribonuclease pancreatic. Chain: a, b, c, d. Synonym: rnase 1, rnase a. Engineered: yes. Mutation: yes
Source: Bos taurus. Bovine. Organism_taxid: 9913. Gene: rnase1, rns1. Expressed in: escherichia coli. Expression_system_taxid: 562
Resolution:
2.18Å     R-factor:   0.181     R-free:   0.249
Authors: A.Merlino,A.Balsamo,L.Mazzarella,F.Sica
Key ref: A.Merlino et al. (2012). Chain termini cross-talk in the swapping process of bovine pancreatic ribonuclease. Biochimie, 94, 1108-1118. PubMed id: 22273774 DOI: 10.1016/j.biochi.2012.01.010
Date:
13-Apr-11     Release date:   15-Feb-12    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P61823  (RNAS1_BOVIN) -  Ribonuclease pancreatic
Seq:
Struc:
150 a.a.
124 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Enzyme reactions 
   Enzyme class: E.C.3.1.27.5  - Pancreatic ribonuclease.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in C-P or U-P with 2',3'-cyclic phosphate intermediates.
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     extracellular region   1 term 
  Biological process     metabolic process   3 terms 
  Biochemical function     nucleic acid binding     7 terms  

 

 
DOI no: 10.1016/j.biochi.2012.01.010 Biochimie 94:1108-1118 (2012)
PubMed id: 22273774  
 
 
Chain termini cross-talk in the swapping process of bovine pancreatic ribonuclease.
A.Merlino, D.Picone, C.Ercole, A.Balsamo, F.Sica.
 
  ABSTRACT  
 
No abstract given.