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PDBsum entry 3rhs

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protein ligands links
Transferase PDB id
3rhs
Jmol
Contents
Protein chain
157 a.a.
Ligands
COA
Waters ×63
PDB id:
3rhs
Name: Transferase
Title: Phosphopantetheine adenylyltransferase from mycobacterium tu complexed with coa
Structure: Phosphopantetheine adenylyltransferase. Chain: a. Synonym: dephospho-coa pyrophosphorylase, pantetheine-phosp adenylyltransferase, ppat. Engineered: yes
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Gene: coad, kdtb, rv2965c, mt3043, mtcy349.22, u0002e. Expressed in: escherichia coli. Expression_system_taxid: 562
Resolution:
1.59Å     R-factor:   0.212     R-free:   0.256
Authors: V.I.Timofeev,E.A.Smirnova,L.A.Chupova,R.S.Esipov,I.P.Kuranov
Key ref: V.I.Timofeev et al. (2012). Three-Dimensional structure of phosphopantetheine adenylyltransferase from mycobacterium. Crystallography reports, 57, 97.
Date:
12-Apr-11     Release date:   11-Apr-12    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P0A530  (COAD_MYCTU) -  Phosphopantetheine adenylyltransferase
Seq:
Struc:
161 a.a.
157 a.a.
Protein chain
Pfam  
P9WPA4  (COAD_MYCTO) - 
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.7.7.3  - Pantetheine-phosphate adenylyltransferase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
Coenzyme A Biosynthesis (late stages)
      Reaction: ATP + pantetheine 4'-phosphate = diphosphate + 3'-dephospho-CoA
ATP
Bound ligand (Het Group name = COA)
matches with 51.92% similarity
+ pantetheine 4'-phosphate
= diphosphate
+ 3'-dephospho-CoA
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   1 term 
  Biological process     biosynthetic process   3 terms 
  Biochemical function     catalytic activity     6 terms