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PDBsum entry 3r7t

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protein ligands metals links
Ligase PDB id
3r7t
Jmol
Contents
Protein chain
408 a.a.
Ligands
CIT
PGE ×2
PEG ×2
GOL
Metals
_CL
Waters ×233
PDB id:
3r7t
Name: Ligase
Title: Crystal structure of adenylosuccinate synthetase from campyl jejuni
Structure: Adenylosuccinate synthetase. Chain: a. Synonym: ampsase, adss, imp-aspartate ligase. Engineered: yes
Source: Campylobacter jejuni. Organism_taxid: 192222. Strain: jejuni nctc 11168. Gene: cj1498c, pura. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Resolution:
2.30Å     R-factor:   0.178     R-free:   0.209
Authors: Y.Kim,M.Gu,K.Kwon,W.F.Anderson,A.Joachimiak,Center For Struc Genomics Of Infectious Diseases (Csgid)
Key ref: Y.Kim et al. Crystal structure of adenylosuccinate synthetase from campylobacter jejuni. To be published, .
Date:
23-Mar-11     Release date:   20-Apr-11    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q9PMG4  (PURA_CAMJE) -  Adenylosuccinate synthetase
Seq:
Struc:
416 a.a.
408 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.6.3.4.4  - Adenylosuccinate synthase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
AMP and GMP Biosynthesis
      Reaction: GTP + IMP + L-aspartate = GDP + phosphate + N6-(1,2-dicarboxyethyl)- AMP
GTP
+ IMP
+
L-aspartate
Bound ligand (Het Group name = CIT)
matches with 57.14% similarity
= GDP
+ phosphate
+ N(6)-(1,2-dicarboxyethyl)- AMP
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   1 term 
  Biological process     'de novo' AMP biosynthetic process   2 terms 
  Biochemical function     nucleotide binding     6 terms