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PDBsum entry 3r23

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protein ligands Protein-protein interface(s) links
Ligase PDB id
3r23
Jmol
Contents
Protein chains
304 a.a.
Ligands
EDO ×4
Waters ×234
PDB id:
3r23
Name: Ligase
Title: Crystal structure of d-alanine--d-alanine ligase from bacill anthracis
Structure: D-alanine--d-alanine ligase. Chain: a, b. Synonym: d-ala-d-ala ligase, d-alanylalanine synthetase. Engineered: yes
Source: Bacillus anthracis. Anthrax,anthrax bacterium. Organism_taxid: 198094. Strain: ames. Gene: bas2435, ba_2610, ddl, ddlb, gbaa_2610. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Resolution:
2.50Å     R-factor:   0.197     R-free:   0.256
Authors: Y.Kim,R.Mulligan,J.Hasseman,W.F.Anderson,A.Joachimiak,Center Structural Genomics Of Infectious Diseases (Csgid)
Key ref: Y.Kim et al. Crystal structure of d-Alanine--D-Alanine ligase from bacillus anthracis. To be published, .
Date:
12-Mar-11     Release date:   30-Mar-11    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q81Q29  (DDL_BACAN) -  D-alanine--D-alanine ligase
Seq:
Struc:
304 a.a.
304 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.6.3.2.4  - D-alanine--D-alanine ligase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
Peptidoglycan Biosynthesis (Part 1)
      Reaction: ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine
ATP
+
2 × D-alanine
Bound ligand (Het Group name = EDO)
matches with 42.86% similarity
= ADP
+ phosphate
+ D-alanyl-D-alanine
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   1 term 
  Biological process     cell wall organization   3 terms 
  Biochemical function     catalytic activity     8 terms