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PDBsum entry 3qx9
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RNA binding protein
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PDB id
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3qx9
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PDB id:
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| Name: |
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RNA binding protein
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Title:
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Crystal structure of mid domain from hago2 in complex with atp
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Structure:
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Protein argonaute-2. Chain: a, b, c. Fragment: unp residues 439-575. Synonym: argonaute2, hago2, eukaryotic translation initiation factor 2c 2, eif-2c 2, eif2c 2, paz piwi domain protein, ppd, protein slicer. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: eif2c2, ago2. Expressed in: escherichia coli. Expression_system_taxid: 562
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Resolution:
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2.00Å
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R-factor:
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0.200
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R-free:
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0.250
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Authors:
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F.Frank,M.R.Fabian,J.Stepinski,J.Jemielity,E.Darzynkiewicz, N.Sonenberg,B.Nagar
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Key ref:
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F.Frank
et al.
(2011).
Structural analysis of 5'-mRNA-cap interactions with the human AGO2 MID domain.
Embo Rep,
12,
415-420.
PubMed id:
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Date:
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01-Mar-11
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Release date:
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20-Apr-11
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PROCHECK
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Headers
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References
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Q9UKV8
(AGO2_HUMAN) -
Protein argonaute-2 from Homo sapiens
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Seq:
Struc:
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859 a.a.
135 a.a.
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Key: |
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Secondary structure |
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CATH domain |
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Embo Rep
12:415-420
(2011)
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PubMed id:
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Structural analysis of 5'-mRNA-cap interactions with the human AGO2 MID domain.
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F.Frank,
M.R.Fabian,
J.Stepinski,
J.Jemielity,
E.Darzynkiewicz,
N.Sonenberg,
B.Nagar.
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ABSTRACT
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Literature references that cite this PDB file's key reference
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PubMed id
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Reference
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M.R.Fabian,
and
N.Sonenberg
(2012).
The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC.
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Nat Struct Mol Biol,
19,
586-593.
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The most recent references are shown first.
Citation data come partly from CiteXplore and partly
from an automated harvesting procedure. Note that this is likely to be
only a partial list as not all journals are covered by
either method. However, we are continually building up the citation data
so more and more references will be included with time.
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Links
