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PDBsum entry 3qpg

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protein ligands metals links
Transferase PDB id
3qpg
Jmol
Contents
Protein chain
396 a.a.
Ligands
SO4 ×8
EDO ×4
3QP
Metals
_CL
Waters ×323
PDB id:
3qpg
Name: Transferase
Title: Crystal structures of escherichia coli aspartate aminotransf reconstituted with 1-deaza-pyridoxal 5'-phosphate: internal and stable l-aspartate external aldimine
Structure: Aspartate transaminase. Chain: a. Engineered: yes
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.79Å     R-factor:   0.149     R-free:   0.179
Authors: W.R.Griswold
Key ref: W.R.Griswold et al. (2011). Crystal structures of aspartate aminotransferase reconstituted with 1-deazapyridoxal 5'-phosphate: internal aldimine and stable L-aspartate external aldimine. Biochemistry, 50, 5918-5924. PubMed id: 21627105 DOI: 10.1021/bi200436y
Date:
13-Feb-11     Release date:   15-Jun-11    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P00509  (AAT_ECOLI) -  Aspartate aminotransferase
Seq:
Struc:
396 a.a.
396 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.6.1.1  - Aspartate transaminase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
L-aspartate
+ 2-oxoglutarate
=
oxaloacetate
Bound ligand (Het Group name = EDO)
matches with 44.44% similarity
+ L-glutamate
      Cofactor: Pyridoxal 5'-phosphate
Pyridoxal 5'-phosphate
Bound ligand (Het Group name = 3QP) matches with 53.85% similarity
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   2 terms 
  Biological process     biosynthetic process   4 terms 
  Biochemical function     catalytic activity     8 terms  

 

 
    reference    
 
 
DOI no: 10.1021/bi200436y Biochemistry 50:5918-5924 (2011)
PubMed id: 21627105  
 
 
Crystal structures of aspartate aminotransferase reconstituted with 1-deazapyridoxal 5'-phosphate: internal aldimine and stable L-aspartate external aldimine.
W.R.Griswold, A.J.Fisher, M.D.Toney.
 
  ABSTRACT  
 
No abstract given.