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PDBsum entry 3ql1

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protein ligands links
Hydrolase PDB id
3ql1
Jmol
Contents
Protein chain
124 a.a.
Ligands
SO4
EDO
ACT
Waters ×97
PDB id:
3ql1
Name: Hydrolase
Title: Crystal structure of ribonuclease a variant a4c/d83e/v118c
Structure: Ribonuclease pancreatic. Chain: a. Synonym: rnase 1, rnase a. Engineered: yes. Mutation: yes
Source: Bos taurus. Bovine. Organism_taxid: 9913. Gene: rnase1, rns1. Expressed in: escherichia coli. Expression_system_taxid: 562
Resolution:
1.29Å     R-factor:   0.155     R-free:   0.190
Authors: U.Arnold,M.Schoepfel
Key ref: U.Arnold and M.Schöpfel (2012). Significant stabilization of ribonuclease A by additive effects. FEBS J, 279, 2508-2519. PubMed id: 22594773
Date:
02-Feb-11     Release date:   29-Feb-12    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P61823  (RNAS1_BOVIN) -  Ribonuclease pancreatic
Seq:
Struc:
150 a.a.
124 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 3 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.3.1.27.5  - Pancreatic ribonuclease.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in C-P or U-P with 2',3'-cyclic phosphate intermediates.
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     extracellular region   1 term 
  Biological process     metabolic process   3 terms 
  Biochemical function     nucleic acid binding     7 terms  

 

 
FEBS J 279:2508-2519 (2012)
PubMed id: 22594773  
 
 
Significant stabilization of ribonuclease A by additive effects.
U.Arnold, M.Schöpfel.
 
  ABSTRACT  
 
No abstract given.