PDBsum entry 3qem

Transport protein

PDB id: 3qem

Contents

Protein chains

355 a.a.

356 a.a.

Ligands

NAG-NAG-BMA-MAN-MAN

NAG ×5

QEM ×2

Metals

_NA ×2

PDB id:

3qem

Name:

Transport protein

Title:

Crystal structure of amino terminal domains of the nmda receptor subunit glun1 and glun2b in complex with ro 25-6981

Structure:

Nmda glutamate receptor subunit. Chain: a, c. Fragment: amino terminal domain, residues 23-405. Engineered: yes. Mutation: yes. Glutamate [nmda] receptor subunit epsilon-2. Chain: b, d. Fragment: amino terminal domain, residues 31-394. Synonym: n-methyl d-aspartate receptor subtype 2b, nmdar2b, nr2b.

Source:

Xenopus laevis. African clawed frog. Organism_taxid: 8355. Gene: grin1, nr1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Rattus norvegicus. Rat. Organism_taxid: 10116.

Resolution:

3.00Å R-factor: 0.195 R-free: 0.250

Authors:

E.Karakas,N.Simorowski,H.Furukawa

Key ref:

E.Karakas et al. (2011). Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors. Nature, 475, 249-253. PubMed id: 21677647

Date:

20-Jan-11 Release date: 15-Jun-11

Protein chains

A0A1L8F5J9  (NMDZ1_XENLA) -  Glutamate receptor ionotropic, NMDA 1 from Xenopus laevis

Seq: 903 a.a.

Struc: 355 a.a.*

Protein chains

Q00960  (NMDE2_RAT) -  Glutamate receptor ionotropic, NMDA 2B from Rattus norvegicus

Seq: 1482 a.a.

Struc: 356 a.a.*

* PDB and UniProt seqs differ at 5 residue positions (black crosses)

Nature 475:249-253 (2011)

PubMed id: 21677647

Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors.

E.Karakas, N.Simorowski, H.Furukawa.

ABSTRACT

No abstract given.