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PDBsum entry 3q37

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protein Protein-protein interface(s) links
Isomerase PDB id
3q37
Jmol
Contents
Protein chains
242 a.a.
Waters ×987
PDB id:
3q37
Name: Isomerase
Title: Identification of amino acids that account for long-range in in proteins using two triosephosphate isomerases from patho trypanosomes.
Structure: Tim from trypanosoma cruzi/ tim from trypanosoma brucei chimera protein. Chain: a, b, c, d. Fragment: unp p04789 residues 2-35 and 92-119, unp p52270 r 35-92 and 121-251. Synonym: tim, triose-phosphate isomerase. Engineered: yes
Source: Trypanosoma cruzi, trypanosoma brucei organism_taxid: 5693, 5702. Gene: tim. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Resolution:
1.65Å     R-factor:   0.191     R-free:   0.220
Authors: I.Garcia-Torres,N.Cabrera,A.Torres-Larios,M.Rodriguez-Bolano A.Gomez-Puyou,R.Perez-Montfort
Key ref: I.García-Torres et al. (2011). Identification of amino acids that account for long-range interactions in two triosephosphate isomerases from pathogenic trypanosomes. PLoS One, 6, e18791. PubMed id: 21533154 DOI: 10.1371/journal.pone.0018791
Date:
21-Dec-10     Release date:   14-Sep-11    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P04789  (TPIS_TRYBB) -  Triosephosphate isomerase, glycosomal
Seq:
Struc:
250 a.a.
242 a.a.*
Protein chains
Pfam   ArchSchema ?
P52270  (TPIS_TRYCR) -  Triosephosphate isomerase, glycosomal
Seq:
Struc:
251 a.a.
242 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 65 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.5.3.1.1  - Triose-phosphate isomerase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: D-glyceraldehyde 3-phosphate = glycerone phosphate
D-glyceraldehyde 3-phosphate
= glycerone phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     metabolic process   2 terms 
  Biochemical function     catalytic activity     2 terms  

 

 
    Added reference    
 
 
DOI no: 10.1371/journal.pone.0018791 PLoS One 6:e18791 (2011)
PubMed id: 21533154  
 
 
Identification of amino acids that account for long-range interactions in two triosephosphate isomerases from pathogenic trypanosomes.
I.García-Torres, N.Cabrera, A.Torres-Larios, M.Rodríguez-Bolaños, S.Díaz-Mazariegos, A.Gómez-Puyou, R.Perez-Montfort.
 
  ABSTRACT  
 
No abstract given.