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PDBsum entry 3py3

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protein links
Transferase PDB id
3py3
Jmol
Contents
Protein chain
357 a.a.
Waters ×242
PDB id:
3py3
Name: Transferase
Title: Crystal structure of phosphorylated p38alpha map kinase
Structure: Mitogen-activated protein kinase 14. Chain: a. Synonym: map kinase 14, mapk 14, crk1, mitogen-activated pr kinase p38 alpha, map kinase p38 alpha. Engineered: yes
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: mapk14, crk1, csbp1, csbp2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.10Å     R-factor:   0.187     R-free:   0.240
Authors: Y.Y.Zhang,J.W.Wu,Z.X.Wang
Key ref: Y.Y.Zhang et al. (2011). Mitogen-activated protein kinase (MAPK) phosphatase 3-mediated cross-talk between MAPKs ERK2 and p38alpha. J Biol Chem, 286, 16150-16162. PubMed id: 21454500 DOI: 10.1074/jbc.M110.203786
Date:
11-Dec-10     Release date:   16-Mar-11    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P47811  (MK14_MOUSE) -  Mitogen-activated protein kinase 14
Seq:
Struc:
360 a.a.
357 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Enzyme reactions 
   Enzyme class: E.C.2.7.11.24  - Mitogen-activated protein kinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: ATP + a protein = ADP + a phosphoprotein
ATP
+ protein
= ADP
+ phosphoprotein
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cell   7 terms 
  Biological process     intracellular signal transduction   40 terms 
  Biochemical function     nucleotide binding     10 terms  

 

 
    reference    
 
 
DOI no: 10.1074/jbc.M110.203786 J Biol Chem 286:16150-16162 (2011)
PubMed id: 21454500  
 
 
Mitogen-activated protein kinase (MAPK) phosphatase 3-mediated cross-talk between MAPKs ERK2 and p38alpha.
Y.Y.Zhang, J.W.Wu, Z.X.Wang.
 
  ABSTRACT  
 
No abstract given.