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PDBsum entry 3pxu

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protein ligands links
Transferase PDB id
3pxu
Jmol
Contents
Protein chain
159 a.a. *
Ligands
COD
GOL ×2
SO4 ×2
Waters ×89
* Residue conservation analysis
PDB id:
3pxu
Name: Transferase
Title: Crystal structure of phosphopantetheine adenylyltransferase burkholderia pseudomallei bound to dephospho-coenzyme a
Structure: Phosphopantetheine adenylyltransferase. Chain: a. Synonym: dephospho-coa pyrophosphorylase, pantetheine-phosp adenylyltransferase, ppat. Engineered: yes
Source: Burkholderia pseudomallei. Organism_taxid: 320372. Strain: 1710b. Gene: burps1710b_0748, coad, coad burps1710b_0748. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.10Å     R-factor:   0.202     R-free:   0.242
Authors: Seattle Structural Genomics Center For Infectious Disease (S
Key ref: T.E.Edwards et al. (2011). Structures of phosphopantetheine adenylyltransferase from Burkholderia pseudomallei. Acta Crystallogr Sect F Struct Biol Cryst Commun, 67, 1032-1037. PubMed id: 21904046
Date:
10-Dec-10     Release date:   22-Dec-10    
Supersedes: 3ikz
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q3JW91  (COAD_BURP1) -  Phosphopantetheine adenylyltransferase
Seq:
Struc:
166 a.a.
159 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.7.7.3  - Pantetheine-phosphate adenylyltransferase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
Coenzyme A Biosynthesis (late stages)
      Reaction: ATP + pantetheine 4'-phosphate = diphosphate + 3'-dephospho-CoA
ATP
Bound ligand (Het Group name = COD)
matches with 56.25% similarity
+ pantetheine 4'-phosphate
= diphosphate
+ 3'-dephospho-CoA
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   1 term 
  Biological process     biosynthetic process   2 terms 
  Biochemical function     catalytic activity     6 terms  

 

 
    reference    
 
 
Acta Crystallogr Sect F Struct Biol Cryst Commun 67:1032-1037 (2011)
PubMed id: 21904046  
 
 
Structures of phosphopantetheine adenylyltransferase from Burkholderia pseudomallei.
T.E.Edwards, D.J.Leibly, J.Bhandari, J.B.Statnekov, I.Phan, S.H.Dieterich, J.Abendroth, B.L.Staker, W.C.Van Voorhis, P.J.Myler, L.J.Stewart.
 
  ABSTRACT  
 
No abstract given.