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PDBsum entry 3pc3

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protein ligands links
Lyase PDB id
3pc3
Jmol
Contents
Protein chain
504 a.a. *
Ligands
HEM
P1T
Waters ×712
* Residue conservation analysis
PDB id:
3pc3
Name: Lyase
Title: Full length structure of cystathionine beta-synthase from dr in complex with aminoacrylate
Structure: Cg1753, isoform a. Chain: a. Synonym: cg1753, isoform b, ld21426p. Engineered: yes
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: cg1753, dmel_cg1753. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Resolution:
1.55Å     R-factor:   0.150     R-free:   0.188
Authors: M.Koutmos,J.L.Smith
Date:
21-Oct-10     Release date:   01-Dec-10    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q9VRD9  (Q9VRD9_DROME) -  Cystathionine beta-synthase, isoform A
Seq:
Struc:
 
Seq:
Struc:
522 a.a.
504 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.4.2.1.22  - Cystathionine beta-synthase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: L-serine + L-homocysteine = L-cystathionine + H2O
L-serine
+ L-homocysteine
= L-cystathionine
+ H(2)O
      Cofactor: Pyridoxal 5'-phosphate
Pyridoxal 5'-phosphate
Bound ligand (Het Group name = P1T) matches with 68.00% similarity
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   1 term 
  Biological process     determination of adult lifespan   3 terms 
  Biochemical function     lyase activity     4 terms