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PDBsum entry 3p9z

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protein ligands links
Ligase PDB id
3p9z
Jmol
Contents
Protein chain
213 a.a. *
Ligands
MLI
Waters ×106
* Residue conservation analysis
PDB id:
3p9z
Name: Ligase
Title: Crystal structure of uroporphyrinogen-iii synthetase from he pylori 26695
Structure: Uroporphyrinogen iii cosynthase (hemd). Chain: a. Engineered: yes
Source: Helicobacter pylori. Organism_taxid: 210. Gene: hp_1224. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.10Å     R-factor:   0.204     R-free:   0.241
Authors: B.Nocek,A.Stein,G.Chhor,R.J.Fenske,K.Buck,A.Joachimiak,Midwe For Structural Genomics (Mcsg)
Key ref: B.Nocek et al. Crystal structure of uroporphyrinogen-Iii synthetase helicobacter pylori 26695. To be published, .
Date:
18-Oct-10     Release date:   03-Nov-10    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
O25822  (O25822_HELPY) -  Uroporphyrinogen III cosynthase (HemD)
Seq:
Struc:
226 a.a.
213 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.4.2.1.75  - Uroporphyrinogen-III synthase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
Porphyrin Biosynthesis (early stages)
      Reaction: Hydroxymethylbilane = uroporphyrinogen III + H2O
Hydroxymethylbilane
= uroporphyrinogen III
+ H(2)O
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     tetrapyrrole biosynthetic process   1 term 
  Biochemical function     lyase activity     2 terms