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PDBsum entry 3p25

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protein ligands metals links
Lyase/inhibitor PDB id
3p25
Jmol
Contents
Protein chain
257 a.a.
Ligands
D02
DMS
Metals
_ZN
Waters ×229
Superseded by: 4dz7
PDB id:
3p25
Name: Lyase/inhibitor
Title: Human carbonic anhydrase ii complexed with 2,3,4,5-tetrafluo sulfonamido-4-(methyl-1,2,3-triazole-4-carboxylate)
Structure: Carbonic anhydrase 2. Chain: a. Synonym: carbonic anhydrase ii, ca-ii, carbonate dehydratas carbonic anhydrasE C, cac. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Resolution:
1.49Å     R-factor:   0.151     R-free:   0.177
Authors: M.Aggarwal,R.Mckenna
Key ref: M.Aggarwal and r.mckenna Human carbonic anhydrase ii complexed with 2,3,4,5-Tetrafluophenyl-1-Sulfonamido-4-(Methyl-1,2,3 triazole-4-Carboxylate). To be published, .
Date:
01-Oct-10     Release date:   19-Oct-11    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P00918  (CAH2_HUMAN) -  Carbonic anhydrase 2
Seq:
Struc:
260 a.a.
257 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.4.2.1.1  - Carbonate dehydratase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: H2CO3 = CO2 + H2O
H(2)CO(3)
= CO(2)
+ H(2)O
      Cofactor: Zinc
Molecule diagrams generated from .mol files obtained from the KEGG ftp site