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PDBsum entry 3p0x

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protein ligands metals Protein-protein interface(s) links
Lyase PDB id
3p0x
Jmol
Contents
Protein chains
422 a.a. *
Ligands
EDO ×6
ICT ×4
Metals
_MG ×4
Waters ×687
* Residue conservation analysis
PDB id:
3p0x
Name: Lyase
Title: Crystal structure of isocitrate lyase from brucella melitens to magnesium isocitrate
Structure: Isocitrate lyase. Chain: a, b, c, d. Synonym: acea. Engineered: yes
Source: Brucella melitensis biovar abortus. Organism_taxid: 359391. Strain: 2308. Gene: acea, bab1_1631, bruab1_1601. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.35Å     R-factor:   0.180     R-free:   0.230
Authors: Seattle Structural Genomics Center For Infectious Disease (S
Key ref: Ssgcid et al. Crystal structure of isocitrate lyase from brucella melitensis, Bound to magnesium isocitrate. To be published, .
Date:
29-Sep-10     Release date:   27-Oct-10    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q2YQA0  (Q2YQA0_BRUA2) -  Isocitrate lyase and phosphorylmutase:Isocitrate lyase
Seq:
Struc:
429 a.a.
422 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.4.1.3.1  - Isocitrate lyase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
Glyoxylate Cycle
      Reaction: Isocitrate = succinate + glyoxylate
Isocitrate
Bound ligand (Het Group name = ICT)
corresponds exactly
= succinate
+
glyoxylate
Bound ligand (Het Group name = EDO)
matches with 80.00% similarity
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     metabolic process   2 terms 
  Biochemical function     catalytic activity     4 terms