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PDBsum entry 3ovb

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protein dna_rna ligands metals Protein-protein interface(s) links
Transferase/RNA PDB id
3ovb
Jmol
Contents
Protein chains
441 a.a. *
DNA/RNA
Ligands
ATP ×3
SO4 ×2
EDO ×5
POP ×2
Metals
_MG ×2
Waters ×475
* Residue conservation analysis
PDB id:
3ovb
Name: Transferase/RNA
Title: How the cca-adding enzyme selects adenine over cytosine in p of tRNA
Structure: Cca-adding enzyme. Chain: a, b. Synonym: tRNA nucleotidyltransferase, tRNA adenylyl-/cytidy transferase, tRNA cca-pyrophosphorylase, tRNA-nt. RNA (35-mer). Chain: c, d. Synonym: tRNA nucleotidyltransferase, tRNA adenylyl-/cytidy transferase, tRNA cca-pyrophosphorylase, tRNA-nt. Engineered: yes
Source: Archaeoglobus fulgidus. Organism_taxid: 2234. Synthetic: yes. Other_details: chemical synthesis
Resolution:
1.95Å     R-factor:   0.213     R-free:   0.248
Authors: B.C.Pan,Y.Xiong,T.A.Steitz
Date:
16-Sep-10     Release date:   01-Dec-10    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
O28126  (CCA_ARCFU) -  CCA-adding enzyme
Seq:
Struc:
437 a.a.
441 a.a.
Key:    PfamA domain  PfamB domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.7.7.72  - Cca tRNA nucleotidyltransferase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: A tRNA precursor + 2 CTP + ATP = a tRNA with a 3' CCA end + 3 diphosphate
tRNA precursor
+ 2 × CTP
+ ATP
= tRNA with a 3' CCA end
+ 3 × diphosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     RNA repair   4 terms 
  Biochemical function     CTP:tRNA cytidylyltransferase activity     13 terms