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PDBsum entry 3oq8

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protein ligands metals Protein-protein interface(s) links
Lyase PDB id
3oq8
Jmol
Contents
Protein chains
424 a.a. *
Ligands
MLA ×4
EDO ×11
Metals
_NA ×9
Waters ×1177
* Residue conservation analysis
PDB id:
3oq8
Name: Lyase
Title: Crystal structure of isocitrate lyase from brucella melitens to the product mimic malonate
Structure: Isocitrate lyase. Chain: a, b, c, d. Engineered: yes
Source: Brucella melitensis biovar abortus. Organism_taxid: 359391. Strain: 2308. Gene: bab1_1631. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.25Å     R-factor:   0.151     R-free:   0.199
Authors: Seattle Structural Genomics Center For Infectious Disease (S
Date:
02-Sep-10     Release date:   15-Sep-10    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q2YQA0  (Q2YQA0_BRUA2) -  Isocitrate lyase and phosphorylmutase:Isocitrate lyase
Seq:
Struc:
429 a.a.
424 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.4.1.3.1  - Isocitrate lyase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
Glyoxylate Cycle
      Reaction: Isocitrate = succinate + glyoxylate
Isocitrate
=
succinate
Bound ligand (Het Group name = MLA)
matches with 50.00% similarity
+ glyoxylate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     metabolic process   2 terms 
  Biochemical function     catalytic activity     4 terms