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PDBsum entry 3op3

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protein ligands links
Hydrolase PDB id
3op3
Jmol
Contents
Protein chain
167 a.a. *
Ligands
SO4 ×4
Waters ×44
* Residue conservation analysis
PDB id:
3op3
Name: Hydrolase
Title: Crystal structure of cell division cycle 25c protein isoform homo sapiens
Structure: M-phase inducer phosphatase 3. Chain: a. Fragment: unp residues 270-462. Synonym: dual specificity phosphatase cdc25c. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cdc25c. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.63Å     R-factor:   0.199     R-free:   0.218
Authors: Y.Kim,A.Weger,C.Hatzos,P.Savitsky,C.Johansson,L.Ball,A.Barr, M.Vollmar,J.Muniz,J.Weigelt,C.H.Arrowsmith,A.Edwards,C.Boun O.Gileadi,F.Von Delft,S.Knapp,A.Joachimiak,Structural Genom Consortium (Sgc)
Key ref: Y.Kim et al. Crystal structure of cell division cycle 25c protein a from homo sapiens. To be published, .
Date:
31-Aug-10     Release date:   29-Sep-10    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P30307  (MPIP3_HUMAN) -  M-phase inducer phosphatase 3
Seq:
Struc:
473 a.a.
167 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.3.1.3.48  - Protein-tyrosine-phosphatase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate
Protein tyrosine phosphate
+ H(2)O
= protein tyrosine
+ phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     intracellular   1 term 
  Biological process     M phase of mitotic cell cycle   2 terms 
  Biochemical function     protein tyrosine phosphatase activity     1 term