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PDBsum entry 3om9

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protein ligands Protein-protein interface(s) links
Oxidoreductase PDB id
3om9
Jmol
Contents
Protein chains
329 a.a. *
Ligands
NAD ×4
OXQ ×4
Waters ×427
* Residue conservation analysis
PDB id:
3om9
Name: Oxidoreductase
Title: T. Gondii bradyzoite-specific ldh (ldh1) in complex with nad
Structure: Lactate dehydrogenase. Chain: a, b, c, d. Engineered: yes
Source: Toxoplasma gondii. Organism_taxid: 5811. Gene: lactate dehydrogenase, tggt1_115280. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Resolution:
1.98Å     R-factor:   0.196     R-free:   0.223
Authors: M.S.Susko,D.K.Wilson
Key ref: M.S.Susko and d.k.wilson T.Gondii bradyzoite-Specific ldh (ldh1) in complex wi and oxq. To be published, .
Date:
26-Aug-10     Release date:   27-Oct-10    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P90613  (P90613_TOXGO) -  Lactate dehydrogenase
Seq:
Struc:
329 a.a.
329 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.1.1.1.27  - L-lactate dehydrogenase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: (S)-lactate + NAD+ = pyruvate + NADH
(S)-lactate
Bound ligand (Het Group name = OXQ)
matches with 50.00% similarity
+
NAD(+)
Bound ligand (Het Group name = NAD)
corresponds exactly
= pyruvate
+ NADH
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     oxidation-reduction process   4 terms 
  Biochemical function     catalytic activity     6 terms