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PDBsum entry 3oks

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protein ligands metals Protein-protein interface(s) links
Transferase PDB id
3oks
Jmol
Contents
Protein chains
444 a.a. *
Ligands
EDO ×9
FMT ×12
Metals
_MG
Waters ×1545
* Residue conservation analysis
PDB id:
3oks
Name: Transferase
Title: Crystal structure of 4-aminobutyrate transaminase from mycob smegmatis
Structure: 4-aminobutyrate transaminase. Chain: a, b, c, d. Engineered: yes
Source: Mycobacterium smegmatis. Organism_taxid: 246196. Strain: atcc 700084/mc(2)155. Gene: gabt, msmeg_2959. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Resolution:
1.80Å     R-factor:   0.128     R-free:   0.159
Authors: Seattle Structural Genomics Center For Infectious Disease (S
Key ref: A.Gardberg et al. Crystal structure of 4-Aminobutyrate transaminase fro mycobacterium smegmatis. To be published, .
Date:
25-Aug-10     Release date:   27-Oct-10    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
A0QWJ0  (A0QWJ0_MYCS2) -  4-aminobutyrate aminotransferase
Seq:
Struc:
446 a.a.
444 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Enzyme reactions 
   Enzyme class: E.C.2.6.1.19  - 4-aminobutyrate--2-oxoglutarate transaminase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate
4-aminobutanoate
Bound ligand (Het Group name = FMT)
matches with 42.00% similarity
+
2-oxoglutarate
Bound ligand (Het Group name = EDO)
matches with 40.00% similarity
= succinate semialdehyde
+ L-glutamate
      Cofactor: Pyridoxal 5'-phosphate
Pyridoxal 5'-phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     gamma-aminobutyric acid metabolic process   1 term 
  Biochemical function     catalytic activity     5 terms