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PDBsum entry 3oig

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protein ligands links
Oxidoreductase/oxidoreductase inhibitor PDB id
3oig
Jmol
Contents
Protein chain
260 a.a.
Ligands
NAD
IMJ
Waters ×265
PDB id:
3oig
Name: Oxidoreductase/oxidoreductase inhibitor
Title: Crystal structure of enoyl-acp reductases i (fabi) from b. S (complex with NAD and inh)
Structure: Enoyl-[acyl-carrier-protein] reductase [nadh]. Chain: a. Synonym: enoyl-acp reductases i, fabi, nadh-dependent enoyl reductase, cold shock-induced protein 15, csi15, vegetative 241, veg241. Engineered: yes
Source: Bacillus subtilis. Organism_taxid: 1423. Strain: 168. Gene: fabi. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Resolution:
1.25Å     R-factor:   0.167     R-free:   0.185
Authors: K.-H.Kim,B.H.Ha,S.J.Kim,S.K.Hong,K.Y.Hwang,E.E.Kim
Key ref: K.H.Kim et al. (2011). Crystal structures of Enoyl-ACP reductases I (FabI) and III (FabL) from B. subtilis. J Mol Biol, 406, 403-415. PubMed id: 21185310 DOI: 10.1016/j.jmb.2010.12.003
Date:
19-Aug-10     Release date:   05-Jan-11    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P54616  (FABI_BACSU) -  Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Seq:
Struc:
258 a.a.
260 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.1.3.1.9  - Enoyl-[acyl-carrier-protein] reductase (NADH).
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: An acyl-[acyl-carrier protein] + NAD+ = a trans-2,3-dehydroacyl-[acyl- carrier protein] + NADH
acyl-[acyl-carrier protein]
+
NAD(+)
Bound ligand (Het Group name = NAD)
corresponds exactly
= trans-2,3-dehydroacyl-[acyl- carrier protein]
+ NADH
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     metabolic process   9 terms 
  Biochemical function     oxidoreductase activity     2 terms  

 

 
    reference    
 
 
DOI no: 10.1016/j.jmb.2010.12.003 J Mol Biol 406:403-415 (2011)
PubMed id: 21185310  
 
 
Crystal structures of Enoyl-ACP reductases I (FabI) and III (FabL) from B. subtilis.
K.H.Kim, B.H.Ha, S.J.Kim, S.K.Hong, K.Y.Hwang, E.E.Kim.
 
  ABSTRACT  
 
No abstract given.