 |
PDBsum entry 3o2d
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Immune system
|
PDB id
|
|
|
|
3o2d
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
Contents |
 |
|
|
|
|
|
|
|
|
|
|
|
216 a.a.
|
|
|
|
|
|
|
|
|
|
|
222 a.a.
|
|
|
|
|
|
|
|
|
|
|
178 a.a.
|
|
|
|
|
|
|
|
|
* Residue conservation analysis
|
|
|
|
|
|
PDB id:
|
|
|
|
| Name: |
|
Immune system
|
|
|
Title:
|
|
Crystal structure of HIV-1 primary receptor cd4 in complex with a potent antiviral antibody
|
|
Structure:
|
|
Ibalizumab light chain. Chain: l. Engineered: yes. Ibalizumab heavy chain. Chain: h. Engineered: yes. T-cell surface glycoprotein cd4. Chain: a. Fragment: unp residues 26-207.
|
|
Source:
|
|
Mus musculus. Mouse. Organism_taxid: 10090. Expressed in: mus musculus. Expression_system_taxid: 10090. Expression_system_cell_line: ns/o. Homo sapiens. Human. Organism_taxid: 9606.
|
|
Resolution:
|
|
|
2.19Å
|
R-factor:
|
0.194
|
R-free:
|
0.224
|
|
|
Authors:
|
|
M.M.Freeman,M.S.Seaman,S.Rits-Volloch,X.Hong,D.D.Ho,B.Chen
|
|
Key ref:
|
|
M.M.Freeman
et al.
(2010).
Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody.
Structure,
18,
1632-1641.
PubMed id:
|
|
|
Date:
|
|
|
22-Jul-10
|
Release date:
|
22-Dec-10
|
|
|
|
|
|
|
PROCHECK
|
|
|
|
|
|
Headers
|
|
|
|
References
|
|
|
|
|
|
|
|
No UniProt id for this chain
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
|
|
|
|
|
|
| |
|
|
Structure
18:1632-1641
(2010)
|
|
PubMed id:
|
|
|
|
|
|
| |
|
Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody.
|
|
M.M.Freeman,
M.S.Seaman,
S.Rits-Volloch,
X.Hong,
C.Y.Kao,
D.D.Ho,
B.Chen.
|
|
|
|
|
| |
ABSTRACT
|
|
|
|
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
 |
 |
|
| |
Links
