PDBsum entry 3nfs

Immune system

PDB id: 3nfs

Contents

Protein chains

212 a.a. *

209 a.a. *

* Residue conservation analysis

PDB id:

3nfs

Name:

Immune system

Title:

Crystal structure the fab fragment of therapeutic antibody daclizumab

Structure:

Heavy chain of fab fragment of daclizumab. Chain: l. Engineered: yes. Light chain of fab fragment of daclizumab. Chain: h. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Other_details: purchased from roche, expressed in a mammalian expression system. Expression system

Resolution:

2.60Å R-factor: 0.227 R-free: 0.275

Authors:

H.Yang,J.Wang,J.Du,C.Zhong,Y.Guo,J.Ding

Key ref:

H.Yang et al. (2010). Structural basis of immunosuppression by the therapeutic antibody daclizumab. Cell Res, 20, 1361-1371. PubMed id: 20820193

Date:

10-Jun-10 Release date: 15-Sep-10

Protein chain

No UniProt id for this chain

Struc: 212 a.a.

Protein chain

No UniProt id for this chain

Struc: 209 a.a.

Cell Res 20:1361-1371 (2010)

PubMed id: 20820193

Structural basis of immunosuppression by the therapeutic antibody daclizumab.

H.Yang, J.Wang, J.Du, C.Zhong, D.Zhang, H.Guo, Y.Guo, J.Ding.

ABSTRACT

No abstract given.