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PDBsum entry 3nav

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protein ligands Protein-protein interface(s) links
Lyase PDB id
3nav
Jmol
Contents
Protein chains
261 a.a. *
Ligands
EDO
Waters ×381
* Residue conservation analysis
PDB id:
3nav
Name: Lyase
Title: Crystal structure of an alpha subunit of tryptophan synthase vibrio cholerae o1 biovar el tor str. N16961
Structure: Tryptophan synthase alpha chain. Chain: a, b. Engineered: yes
Source: Vibrio cholerae o1 biovar el tor. Organism_taxid: 243277. Strain: n16961. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Resolution:
2.10Å     R-factor:   0.182     R-free:   0.233
Authors: B.Nocek,M.Makowska-Grzyska,K.Kwon,A.Anderson,A.Joachimiak,Cs
Key ref: B.Nocek et al. Crystal structure of an alpha subunit of tryptophan synthase from vibrio cholerae o1 biovar el tor str. N. To be published, .
Date:
02-Jun-10     Release date:   30-Jun-10    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
C3LLL5  (TRPA_VIBCM) -  Tryptophan synthase alpha chain
Seq:
Struc:
268 a.a.
261 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.4.2.1.20  - Tryptophan synthase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
Tryptophan Biosynthesis
      Reaction: L-serine + 1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + D-glyceraldehyde 3-phosphate + H2O
L-serine
+ 1-C-(indol-3-yl)glycerol 3-phosphate
= L-tryptophan
+
D-glyceraldehyde 3-phosphate
Bound ligand (Het Group name = EDO)
matches with 40.00% similarity
+ H(2)O
      Cofactor: Pyridoxal 5'-phosphate
Pyridoxal 5'-phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     metabolic process   5 terms 
  Biochemical function     catalytic activity     3 terms