spacer
spacer

PDBsum entry 3mvd

Go to PDB code: 
protein dna_rna Protein-protein interface(s) links
Signaling protein/structural protein/DNA PDB id
3mvd
Jmol
Contents
Protein chains
98 a.a. *
82 a.a. *
107 a.a. *
93 a.a. *
391 a.a. *
DNA/RNA
* Residue conservation analysis
PDB id:
3mvd
Name: Signaling protein/structural protein/DNA
Title: Crystal structure of the chromatin factor rcc1 in complex wi nucleosome core particle
Structure: Histone h3.2. Chain: a, e. Engineered: yes. Histone h4. Chain: b, f. Engineered: yes. Histone h2a. Chain: c, g. Engineered: yes.
Source: Xenopus laevis. Clawed frog,common platanna,platanna. Organism_taxid: 8355. Gene: histone h3. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: histone h4. Gene: loc494591. Gene: histone h2b.
Resolution:
2.90Å     R-factor:   0.176     R-free:   0.215
Authors: R.D.Makde,J.R.England,H.P.Yennawar,S.Tan
Key ref: R.D.Makde et al. (2010). Structure of RCC1 chromatin factor bound to the nucleosome core particle. Nature, 467, 562-566. PubMed id: 20739938
Date:
04-May-10     Release date:   25-Aug-10    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P84233  (H32_XENLA) -  Histone H3.2
Seq:
Struc:
136 a.a.
98 a.a.*
Protein chains
Pfam   ArchSchema ?
P62799  (H4_XENLA) -  Histone H4
Seq:
Struc:
103 a.a.
82 a.a.
Protein chains
Pfam   ArchSchema ?
Q6AZJ8  (Q6AZJ8_XENLA) -  Histone H2A
Seq:
Struc:
130 a.a.
107 a.a.
Protein chains
Pfam   ArchSchema ?
P02281  (H2B11_XENLA) -  Histone H2B 1.1
Seq:
Struc:
126 a.a.
93 a.a.*
Protein chains
Pfam   ArchSchema ?
P25171  (RCC1_DROME) -  Regulator of chromosome condensation
Seq:
Struc:
 
Seq:
Struc:
547 a.a.
391 a.a.
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 2 residue positions (black crosses)

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     nucleus   4 terms 
  Biological process     nucleosome assembly   1 term 
  Biochemical function     protein binding     3 terms  

 

 
Nature 467:562-566 (2010)
PubMed id: 20739938  
 
 
Structure of RCC1 chromatin factor bound to the nucleosome core particle.
R.D.Makde, J.R.England, H.P.Yennawar, S.Tan.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
23202585 F.Mueller-Planitz, H.Klinker, J.Ludwigsen, and P.B.Becker (2013).
The ATPase domain of ISWI is an autonomous nucleosome remodeling machine.
  Nat Struct Mol Biol, 20, 82-89.  
22722606 K.Luger, M.L.Dechassa, and D.J.Tremethick (2012).
New insights into nucleosome and chromatin structure: an ordered state or a disordered affair?
  Nat Rev Mol Cell Biol, 13, 436-447.  
21332355 A.J.Andrews, and K.Luger (2011).
Nucleosome structure(s) and stability: variations on a theme.
  Annu Rev Biophys, 40, 99.  
21320770 A.Stein, R.Mosca, and P.Aloy (2011).
Three-dimensional modeling of protein interactions and complexes is going 'omics.
  Curr Opin Struct Biol, 21, 200-208.  
  21344528 B.Wu, M.S.Ong, M.Groessl, Z.Adhireksan, C.G.Hartinger, P.J.Dyson, and C.A.Davey (2011).
A ruthenium antimetastasis agent forms specific histone protein adducts in the nucleosome core.
  Chemistry, 17, 3562-3566.
PDB code: 3mnn
  21410646 F.J.Blanco, and G.Montoya (2011).
Transient DNA / RNA-protein interactions.
  FEBS J, 278, 1643-1650.  
21093592 F.Wu, Y.Liu, Z.Zhu, H.Huang, B.Ding, J.Wu, and Y.Shi (2011).
The 1.9Å crystal structure of Prp20p from Saccharomyces cerevisiae and its binding properties to Gsp1p and histones.
  J Struct Biol, 174, 213-222.
PDB code: 3of7
21392507 G.Cavalli (2011).
From Linear Genes to Epigenetic Inheritance of Three-dimensional Epigenomes.
  J Mol Biol, 409, 54-61.  
21424324 H.Zhang, and R.K.Dawe (2011).
Mechanisms of plant spindle formation.
  Chromosome Res, 19, 335-344.  
21525927 K.Yamada, T.D.Frouws, B.Angst, D.J.Fitzgerald, C.DeLuca, K.Schimmele, D.F.Sargent, and T.J.Richmond (2011).
Structure and mechanism of the chromatin remodelling factor ISW1a.
  Nature, 472, 448-453.
PDB codes: 2y9y 2y9z
21176878 S.Tan, and C.A.Davey (2011).
Nucleosome structural studies.
  Curr Opin Struct Biol, 21, 128-136.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time. Where a reference describes a PDB structure, the PDB code is shown on the right.