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PDBsum entry 3mtl

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protein ligands links
Transferase PDB id
3mtl
Jmol
Contents
Protein chain
294 a.a. *
Ligands
FEF
Waters ×101
* Residue conservation analysis
PDB id:
3mtl
Name: Transferase
Title: Crystal structure of the pctaire1 kinase in complex with ind e804
Structure: Cell division protein kinase 16. Chain: a. Fragment: residues in unp 163-478. Synonym: serine/threonine-protein kinase pctaire-1, pctaire protein kinase 1. Engineered: yes. Mutation: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.40Å     R-factor:   0.198     R-free:   0.263
Authors: T.Krojer,T.D.Sharpe,A.Roos,P.Savitsky,A.Amos,V.Ayinampudi,G. O.Fedorov,T.Keates,C.Phillips,N.Burgess-Brown,Y.Zhang,A.C.W J.Muniz,M.Vollmar,C.Thangaratnarajah,P.Rellos,E.Ugochukwu, P.Filippakopoulos,W.Yue,S.Das,F.Von Delft,A.Edwards,C.H.Arr J.Weigelt,C.Bountra,S.Knapp,A.Bullock,Structural Genomics C (Sgc)
Key ref: T.Krojer et al. Crystal structure of the pctaire1 kinase in complex w indirubin e804. To be published, .
Date:
30-Apr-10     Release date:   09-Jun-10    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q00536  (CDK16_HUMAN) -  Cyclin-dependent kinase 16
Seq:
Struc:
496 a.a.
294 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Enzyme reactions 
   Enzyme class: E.C.2.7.11.22  - Cyclin-dependent kinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: ATP + a protein = ADP + a phosphoprotein
ATP
+ protein
= ADP
+ phosphoprotein
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     protein phosphorylation   1 term 
  Biochemical function     transferase activity, transferring phosphorus-containing groups     4 terms