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PDBsum entry 3mrz

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protein dna_rna metals Protein-protein interface(s) links
Ribosome PDB id
3mrz
Jmol
Contents
Protein chains
271 a.a. *
204 a.a. *
202 a.a. *
181 a.a. *
159 a.a. *
145 a.a. *
32 a.a. *
137 a.a. *
122 a.a. *
146 a.a. *
136 a.a. *
117 a.a. *
98 a.a. *
137 a.a. *
116 a.a. *
101 a.a. *
112 a.a. *
92 a.a. *
100 a.a. *
188 a.a. *
76 a.a. *
88 a.a. *
62 a.a. *
59 a.a. *
30 a.a. *
52 a.a. *
44 a.a. *
48 a.a. *
63 a.a. *
DNA/RNA
Metals
_MG ×160
* Residue conservation analysis
PDB id:
3mrz
Name: Ribosome
Title: Recognition of the amber stop codon by release factor rf1. T 3mrz contains 50s ribosomal subunit. The 30s ribosomal subu found in PDB entry 3ms0. Molecule a in the same asymmetric deposited as 3mr8 (50s) and 3ms1 (30s).
Structure: 23s ribosomal RNA. Chain: a. 5s ribosomal RNA. Chain: b. 50s ribosomal protein l2. Chain: c. 50s ribosomal protein l3. Chain: d. 50s ribosomal protein l4.
Source: Thermus thermophilus. Organism_taxid: 262724. Strain: hb27. Strain: hb27
Resolution:
3.62Å     R-factor:   0.260     R-free:   0.291
Authors: A.Korostelev,J.Zhu,H.Asahara,H.F.Noller
Key ref: A.Korostelev et al. (2010). Recognition of the amber uag stop codon by release fa rf1.. Embo j., 29, 2577. PubMed id: 20588254
Date:
29-Apr-10     Release date:   14-Jul-10    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q72I07  (RL2_THET2) -  50S ribosomal protein L2
Seq:
Struc:
276 a.a.
271 a.a.
Protein chain
Pfam   ArchSchema ?
Q72I04  (RL3_THET2) -  50S ribosomal protein L3
Seq:
Struc:
206 a.a.
204 a.a.
Protein chain
Pfam   ArchSchema ?
Q72I05  (RL4_THET2) -  50S ribosomal protein L4
Seq:
Struc:
205 a.a.
202 a.a.
Protein chain
Pfam   ArchSchema ?
Q72I16  (RL5_THET2) -  50S ribosomal protein L5
Seq:
Struc:
182 a.a.
181 a.a.
Protein chain
Pfam   ArchSchema ?
Q72I19  (RL6_THET2) -  50S ribosomal protein L6
Seq:
Struc:
180 a.a.
159 a.a.
Protein chain
Pfam   ArchSchema ?
Q72GV5  (RL9_THET2) -  50S ribosomal protein L9
Seq:
Struc:
148 a.a.
145 a.a.
Protein chain
Pfam   ArchSchema ?
Q72GS1  (RL10_THET2) -  50S ribosomal protein L10
Seq:
Struc:
173 a.a.
32 a.a.*
Protein chain
Pfam   ArchSchema ?
Q72IN1  (RL13_THET2) -  50S ribosomal protein L13
Seq:
Struc:
140 a.a.
137 a.a.
Protein chain
Pfam   ArchSchema ?
Q72I14  (RL14_THET2) -  50S ribosomal protein L14
Seq:
Struc:
122 a.a.
122 a.a.
Protein chain
Pfam   ArchSchema ?
Q72I23  (RL15_THET2) -  50S ribosomal protein L15
Seq:
Struc:
150 a.a.
146 a.a.
Protein chain
Pfam   ArchSchema ?
Q72I11  (RL16_THET2) -  50S ribosomal protein L16
Seq:
Struc:
141 a.a.
136 a.a.
Protein chain
Pfam   ArchSchema ?
Q72I33  (RL17_THET2) -  50S ribosomal protein L17
Seq:
Struc:
118 a.a.
117 a.a.
Protein chain
Pfam   ArchSchema ?
Q72I20  (RL18_THET2) -  50S ribosomal protein L18
Seq:
Struc:
112 a.a.
98 a.a.
Protein chain
Pfam   ArchSchema ?
Q72JU9  (RL19_THET2) -  50S ribosomal protein L19
Seq:
Struc:
146 a.a.
137 a.a.
Protein chain
Pfam   ArchSchema ?
Q72L76  (RL20_THET2) -  50S ribosomal protein L20
Seq:
Struc:
118 a.a.
116 a.a.
Protein chain
Pfam   ArchSchema ?
Q72HR2  (RL21_THET2) -  50S ribosomal protein L21
Seq:
Struc:
101 a.a.
101 a.a.
Protein chain
Pfam   ArchSchema ?
Q72I09  (RL22_THET2) -  50S ribosomal protein L22
Seq:
Struc:
113 a.a.
112 a.a.
Protein chain
Pfam   ArchSchema ?
Q72I06  (RL23_THET2) -  50S ribosomal protein L23
Seq:
Struc:
96 a.a.
92 a.a.
Protein chain
Pfam   ArchSchema ?
Q72I15  (RL24_THET2) -  50S ribosomal protein L24
Seq:
Struc:
110 a.a.
100 a.a.
Protein chain
Pfam   ArchSchema ?
Q72IA7  (RL25_THET2) -  50S ribosomal protein L25
Seq:
Struc:
206 a.a.
188 a.a.
Protein chain
Pfam   ArchSchema ?
Q72HR3  (RL27_THET2) -  50S ribosomal protein L27
Seq:
Struc:
85 a.a.
76 a.a.
Protein chain
Pfam   ArchSchema ?
Q72G84  (RL28_THET2) -  50S ribosomal protein L28
Seq:
Struc:
98 a.a.
88 a.a.
Protein chain
Pfam   ArchSchema ?
Q72I12  (RL29_THET2) -  50S ribosomal protein L29
Seq:
Struc:
72 a.a.
62 a.a.
Protein chain
Pfam   ArchSchema ?
Q72I22  (RL30_THET2) -  50S ribosomal protein L30
Seq:
Struc:
60 a.a.
59 a.a.
Protein chain
Pfam   ArchSchema ?
Q72JR0  (RL31_THET2) -  50S ribosomal protein L31
Seq:
Struc:
71 a.a.
30 a.a.
Protein chain
Pfam   ArchSchema ?
P62652  (RL32_THET2) -  50S ribosomal protein L32
Seq:
Struc:
60 a.a.
52 a.a.
Protein chain
Pfam   ArchSchema ?
Q72GW3  (RL33_THET2) -  50S ribosomal protein L33
Seq:
Struc:
54 a.a.
44 a.a.
Protein chain
Pfam   ArchSchema ?
P80340  (RL34_THET8) -  50S ribosomal protein L34
Seq:
Struc:
49 a.a.
48 a.a.
Protein chain
Pfam   ArchSchema ?
Q72L77  (RL35_THET2) -  50S ribosomal protein L35
Seq:
Struc:
65 a.a.
63 a.a.
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 12 residue positions (black crosses)

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     intracellular   4 terms 
  Biological process     ribosome biogenesis   2 terms 
  Biochemical function     structural constituent of ribosome     9 terms  

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
21420300 B.P.Klaholz (2011).
Molecular recognition and catalysis in translation termination complexes.
  Trends Biochem Sci, 36, 282-292.  
21281690 K.Kipper, S.Sild, C.Hetényi, J.Remme, and A.Liiv (2011).
Pseudouridylation of 23S rRNA helix 69 promotes peptide release by release factor RF2 but not by release factor RF1.
  Biochimie, 93, 834-844.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time.