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PDBsum entry 3meb

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protein ligands Protein-protein interface(s) links
Transferase PDB id
3meb
Jmol
Contents
Protein chains
426 a.a. *
Ligands
SO4 ×4
PLP ×2
EDO ×14
Waters ×809
* Residue conservation analysis
PDB id:
3meb
Name: Transferase
Title: Structure of cytoplasmic aspartate aminotransferase from gia lamblia
Structure: Aspartate aminotransferase. Chain: a, b. Engineered: yes
Source: Giardia lamblia. Organism_taxid: 184922. Strain: atcc 50803. Gene: gl50803_91056. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.90Å     R-factor:   0.176     R-free:   0.214
Authors: Seattle Structural Genomics Center For Infectious Disease (S
Key ref: Seattle structural genomics center for infectiousdisease (ssgcid) et al. Structure of cytoplasmic aspartate aminotransferase from giardia lamblia. To be published, .
Date:
31-Mar-10     Release date:   21-Apr-10    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
A8B1V5  (A8B1V5_GIAIC) -  Aspartate aminotransferase
Seq:
Struc:
427 a.a.
426 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.6.1.1  - Aspartate transaminase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
L-aspartate
+ 2-oxoglutarate
=
oxaloacetate
Bound ligand (Het Group name = EDO)
matches with 44.44% similarity
+ L-glutamate
      Cofactor: Pyridoxal 5'-phosphate
Pyridoxal 5'-phosphate
Bound ligand (Het Group name = PLP) corresponds exactly
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     biosynthetic process   2 terms 
  Biochemical function     catalytic activity     6 terms