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PDBsum entry 3mbb

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protein ligands metals Protein-protein interface(s) links
Lyase PDB id
3mbb
Jmol
Contents
Protein chains
451 a.a. *
Ligands
PO4 ×4
EDO
Metals
_NA
Waters ×577
* Residue conservation analysis
PDB id:
3mbb
Name: Lyase
Title: Crystal structure of stspl - apo form, after treatment with semicarbazide
Structure: Putative sphingosine-1-phosphate lyase. Chain: a, b. Engineered: yes
Source: Symbiobacterium thermophilum. Organism_taxid: 2734. Gene: sth1274. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.05Å     R-factor:   0.182     R-free:   0.218
Authors: F.Bourquin,M.G.Grutter,G.Capitani
Key ref: F.Bourquin et al. (2010). Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism. Structure, 18, 1054-1065. PubMed id: 20696404
Date:
25-Mar-10     Release date:   18-Aug-10    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q67PY4  (Q67PY4_SYMTH) -  Putative sphingosine-1-phosphate lyase
Seq:
Struc:
507 a.a.
451 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     carboxylic acid metabolic process   1 term 
  Biochemical function     catalytic activity     5 terms  

 

 
Structure 18:1054-1065 (2010)
PubMed id: 20696404  
 
 
Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism.
F.Bourquin, H.Riezman, G.Capitani, M.G.Grütter.
 
  ABSTRACT  
 
No abstract given.