PDBsum entry 3m4z

Lyase

PDB id: 3m4z

Contents

Protein chain

309 a.a. *

Metals

_CL ×2

_CO

_MG ×3

Waters ×227

* Residue conservation analysis

PDB id:

3m4z

Name:

Lyase

Title:

Crystal structure of b. Subtilis ferrochelatase with cobalt bound at the active site

Structure:

Ferrochelatase. Chain: a. Synonym: protoheme ferro-lyase, heme synthase. Engineered: yes

Source:

Bacillus subtilis. Organism_taxid: 1423. Gene: hemf, hemh. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.94Å R-factor: 0.170 R-free: 0.199

Authors:

C.A.G.Soderberg,M.D.Hansson,R.Sreekanth,S.Al-Karadaghi,M.Hansson

Key ref:

M.D.Hansson et al. Bacterial ferrochelatase goes human: tyr13 determines apparent metal specificity of bacillus subtilis ferrochelatase. To be published, .

Date:

12-Mar-10 Release date: 10-Nov-10

Protein chain

P32396  (HEMH_BACSU) -  Coproporphyrin III ferrochelatase from Bacillus subtilis (strain 168)

Seq: 310 a.a.

Struc: 309 a.a.

Enzyme reactions

• Enzyme class: E.C.4.99.1.9 - coproporphyrin ferrochelatase.
• Reaction: Fe-coproporphyrin III + 2 H⁺ = coproporphyrin III + Fe²⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site