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PDBsum entry 3m3d

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protein ligands metals links
Hydrolase PDB id
3m3d
Jmol
Contents
Protein chain
532 a.a.
Ligands
NAG ×2
PG4
PEG ×6
Metals
_XE ×2
Waters ×210
PDB id:
3m3d
Name: Hydrolase
Title: Crystal structure of acetylcholinesterase in complex with xe
Structure: Acetylcholinesterase. Chain: a. Fragment: unp residues 22-564. Synonym: ache. Ec: 3.1.1.7
Source: Torpedo californica. Pacific electric ray. Organism_taxid: 7787
Resolution:
2.34Å     R-factor:   0.209     R-free:   0.200
Authors: J.Behnen,B.Brumshtein,L.Toker,I Silman,J.L.Sussman,G.Klebe,A
Key ref: J.Behnen et al. Old acquantance rediscover. To be published, .
Date:
09-Mar-10     Release date:   09-Mar-11    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P04058  (ACES_TORCA) -  Acetylcholinesterase
Seq:
Struc:
 
Seq:
Struc:
586 a.a.
532 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.3.1.1.7  - Acetylcholinesterase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Acetylcholine + H2O = choline + acetate
Acetylcholine
Bound ligand (Het Group name = NAG)
matches with 41.18% similarity
+ H(2)O
= choline
+ acetate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     synapse   5 terms 
  Biological process     neurotransmitter catabolic process   2 terms 
  Biochemical function     carboxylic ester hydrolase activity     4 terms