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PDBsum entry 3lf5

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protein ligands Protein-protein interface(s) links
Oxidoreductase PDB id
3lf5
Jmol
Contents
Protein chains
87 a.a. *
Ligands
HEM ×2
SO4 ×2
Waters ×145
* Residue conservation analysis
PDB id:
3lf5
Name: Oxidoreductase
Title: Structure of human nadh cytochrome b5 oxidoreductase (ncb5or domain to 1.25a resolution
Structure: Cytochrome b5 reductase 4. Chain: a, b. Fragment: unp residues 51-137. Synonym: flavohemoprotein b5/b5r, b5+b5r, cb5/cb5r, n-termi cytochrome b5 and cytochrome b5 oxidoreductase domain-conta protein. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cyb5r4, ncb5or. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.25Å     R-factor:   0.147     R-free:   0.173
Authors: B.Deng,S.Parthasarathy,W.Wang,B.R.Gibney,K.P.Battaile,S.Love D.R.Benson,H.Zhu
Key ref: B.Deng et al. Unique heme pocket in human ncb5or and structural bas inter-Domain electron transfer. To be published, .
Date:
15-Jan-10     Release date:   14-Jul-10    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q7L1T6  (NB5R4_HUMAN) -  Cytochrome b5 reductase 4
Seq:
Struc:
 
Seq:
Struc:
521 a.a.
87 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.1.6.2.2  - Cytochrome-b5 reductase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: NADH + 2 ferricytochrome b5 = NAD+ + H+ + 2 ferrocytochrome b5
NADH
+ 2 × ferricytochrome b5
= NAD(+)
+ H(+)
+ 2 × ferrocytochrome b5
      Cofactor: FAD
FAD
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biochemical function     heme binding     1 term