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PDBsum entry 3l92

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protein ligands links
Transferase PDB id
3l92
Jmol
Contents
Protein chain
159 a.a. *
Ligands
COA
Waters ×166
* Residue conservation analysis
PDB id:
3l92
Name: Transferase
Title: Phosphopantetheine adenylyltransferase from yersinia pestis with coenzyme a.
Structure: Phosphopantetheine adenylyltransferase. Chain: a. Synonym: pantetheine-phosphate adenylyltransferase, ppat, d coa pyrophosphorylase. Engineered: yes
Source: Yersinia pestis. Organism_taxid: 214092. Strain: co92. Gene: coad, kdtb, y0088, ypo0053, yp_0054. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Resolution:
1.89Å     R-factor:   0.165     R-free:   0.192
Authors: J.Osipiuk,N.Maltseva,M.Makowska-Grzyska,K.Kwon,W.F.Anderson, A.Joachimiak,Csgid
Key ref: J.Osipiuk et al. X-Ray crystal structure of phosphopantetheine adenylyltransferase from yersinia pestis.. To be published, .
Date:
04-Jan-10     Release date:   19-Jan-10    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q8ZJN9  (COAD_YERPE) -  Phosphopantetheine adenylyltransferase
Seq:
Struc:
159 a.a.
159 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.7.7.3  - Pantetheine-phosphate adenylyltransferase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
Coenzyme A Biosynthesis (late stages)
      Reaction: ATP + pantetheine 4'-phosphate = diphosphate + 3'-dephospho-CoA
ATP
Bound ligand (Het Group name = COA)
matches with 51.92% similarity
+ pantetheine 4'-phosphate
= diphosphate
+ 3'-dephospho-CoA
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   1 term 
  Biological process     biosynthetic process   2 terms 
  Biochemical function     catalytic activity     6 terms