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PDBsum entry 3l74

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protein ligands Protein-protein interface(s) links
Oxidoreductase PDB id
3l74
Jmol
Contents
Protein chains
443 a.a. *
421 a.a. *
380 a.a. *
241 a.a. *
196 a.a. *
101 a.a. *
81 a.a. *
70 a.a. *
46 a.a. *
61 a.a. *
Ligands
PEE ×6
UNL ×11
HEM ×4
FMX ×2
_UQ ×2
AZI ×2
BOG ×6
HEC ×2
CDL ×4
FES ×2
Waters ×28
* Residue conservation analysis
PDB id:
3l74
Name: Oxidoreductase
Title: Cytochrome bc1 complex from chicken with famoxadone bound
Structure: Mitochondrial ubiquinol-cytochromE-C reductase co protein i. Chain: a, n. Mitochondrial ubiquinol-cytochromE-C reductase co protein 2. Chain: b, o. Cytochrome b. Chain: c, p. Synonym: ubiquinol-cytochromE-C reductase complex cytochrom
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Organism_taxid: 9031
Resolution:
2.76Å     R-factor:   0.259     R-free:   0.286
Authors: L.Huang,E.A.Berry
Key ref: L.Huang and e.a.berry Famoxadone and related inhibitors bind like methoxy acrylate inhibitors in the qo site of the bc1 compl and fix the rieske iron-Sulfur protein in a positio close to but distinct from that seen with stigmatellin and other "distal" qo inhibitors.. To be published, .
Date:
28-Dec-09     Release date:   02-Feb-10    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
D0VX31  (D0VX31_CHICK) -  Mitochondrial ubiquinol-cytochrome-c reductase complex core protein i
Seq:
Struc:
446 a.a.
443 a.a.
Protein chains
Pfam   ArchSchema ?
D0VX29  (D0VX29_CHICK) -  Mitochondrial ubiquinol-cytochrome-c reductase complex core protein 2
Seq:
Struc:
441 a.a.
421 a.a.
Protein chains
Pfam   ArchSchema ?
P18946  (CYB_CHICK) -  Cytochrome b
Seq:
Struc:
380 a.a.
380 a.a.
Protein chains
Pfam   ArchSchema ?
D0VX26  (D0VX26_CHICK) -  Mitochondrial cytochrome c1, heme protein
Seq:
Struc:
241 a.a.
241 a.a.
Protein chains
Pfam   ArchSchema ?
Q5ZLR5  (UCRI_CHICK) -  Cytochrome b-c1 complex subunit Rieske, mitochondrial
Seq:
Struc:
272 a.a.
196 a.a.
Protein chains
Pfam   ArchSchema ?
D0VX30  (D0VX30_CHICK) -  Cytochrome b-c1 complex subunit 7
Seq:
Struc:
110 a.a.
101 a.a.
Protein chains
Pfam   ArchSchema ?
D0VX32  (D0VX32_CHICK) -  Mitochondrial ubiquinol-cytochrome c reductase ubiquinone-binding protein qp-c
Seq:
Struc:
81 a.a.
81 a.a.
Protein chains
Pfam   ArchSchema ?
D0VX28  (D0VX28_CHICK) -  Cytochrome b-c1 complex subunit 6
Seq:
Struc:
77 a.a.
70 a.a.
Protein chains
Pfam   ArchSchema ?
Q5ZLR5  (UCRI_CHICK) -  Cytochrome b-c1 complex subunit Rieske, mitochondrial
Seq:
Struc:
272 a.a.
46 a.a.*
Protein chains
Pfam   ArchSchema ?
D0VX27  (D0VX27_CHICK) -  Mitochondrial ubiquinol-cytochrome c reductase 7.2 kda protein
Seq:
Struc:
61 a.a.
61 a.a.
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 15 residue positions (black crosses)

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     membrane   8 terms 
  Biological process     mitochondrial electron transport, ubiquinol to cytochrome c   5 terms 
  Biochemical function     catalytic activity     9 terms