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PDBsum entry 3ki1

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protein ligands links
Transferase,toxin PDB id
3ki1
Jmol
Contents
Protein chain
196 a.a.
Ligands
G9F ×2
Waters ×261
PDB id:
3ki1
Name: Transferase,toxin
Title: Catalytic fragment of cholix toxin from vibrio cholerae in c with inhibitor gp-f
Structure: Cholix toxin. Chain: a. Fragment: catalytic domain, residues 459-665. Engineered: yes
Source: Vibrio cholerae. Organism_taxid: 666. Strain: tp. Gene: chxa, toxa. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.43Å     R-factor:   0.177     R-free:   0.203
Authors: R.Jorgensen,P.R.Edwards,A.R.Merrill
Key ref: R.Jorgensen et al. Structure function analysis of soluble inhibitors of toxin from vibrio cholerae. To be published, .
Date:
31-Oct-09     Release date:   27-Oct-10    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q5EK40  (CHXA_VIBCL) -  Cholix toxin
Seq:
Struc:
 
Seq:
Struc:
666 a.a.
196 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 4 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.2.4.2.36  - NAD(+)--diphthamide ADP-ribosyltransferase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: NAD+ + diphthamide-[translation elongation factor 2] = nicotinamide + N-(ADP-D-ribosyl)diphthamide-[translation elongation factor 2]
NAD(+)
+ diphthamide-[translation elongation factor 2]
= nicotinamide
+ N-(ADP-D-ribosyl)diphthamide-[translation elongation factor 2]
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biochemical function     NAD+-diphthamide ADP-ribosyltransferase activity     1 term