PDBsum entry: 3k2o

Oxidoreductase

PDB id: 3k2o

Contents

Protein chains

335 a.a. *

Ligands

PO4 ×3

ACT ×2

GOL

Metals

_NI ×2

_NA ×2

_CL ×6

Waters ×673

* Residue conservation analysis

PDB id:

3k2o

Name:

Oxidoreductase

Title:

Structure of an oxygenase

Structure:

Bifunctional arginine demethylase and lysyl-hydro jmjd6. Chain: a, b. Fragment: unp residues 2-335. Synonym: histone arginine demethylase jmjd6, peptide-lysine dioxygenase jmjd6, lysyl-hydroxylase jmjd6, jmjc domain-con protein 6, jumonji domain-containing protein 6, phosphatidy receptor, protein ptdsr. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: jmjd6, kiaa0585, ptdsr. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

1.75Å R-factor: 0.194 R-free: 0.225

Authors:

T.Krojer,M.A.Mcdonough,I.J.Clifton,M.Mantri,S.S.Ng,A.C.W.Pik D.S.Butler,C.J.Webby,G.Kochan,C.Bhatia,J.E.Bray,A.Chaikuad, O.Gileadi,F.Von Delft,J.Weigelt,C.H.Arrowsmith,C.Bountra, A.M.Edwards,C.J.Schofield,K.L.Kavanagh,U.Oppermann

Key ref:

M.Mantri et al. (2010). Crystal Structure of the 2-Oxoglutarate- and Fe(II)-Dependent Lysyl Hydroxylase JMJD6. J Mol Biol, 401, 211-222. PubMed id: 20685276 DOI: 10.1016/j.jmb.2010.05.054

Date:

30-Sep-09 Release date: 03-Nov-09

Protein chains

Q6NYC1  (JMJD6_HUMAN) -  Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

Seq: 403 a.a.

Struc: 335 a.a.

 Gene Ontology (GO) functional annotation 

• Biochemical function: protein binding (1 term)

DOI no: 10.1016/j.jmb.2010.05.054

J Mol Biol 401:211-222 (2010)

PubMed id: 20685276

Crystal Structure of the 2-Oxoglutarate- and Fe(II)-Dependent Lysyl Hydroxylase JMJD6.

M.Mantri, T.Krojer, E.A.Bagg, C.A.Webby, D.S.Butler, G.Kochan, K.L.Kavanagh, U.Oppermann, M.A.McDonough, C.J.Schofield.

ABSTRACT

No abstract given.