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PDBsum entry 3isd

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protein dna_rna ligands metals links
Transferase/DNA PDB id
3isd
Jmol
Contents
Protein chain
326 a.a. *
DNA/RNA
Ligands
F2A
EDO
Metals
_NA ×3
_MN ×8
Waters ×268
* Residue conservation analysis
PDB id:
3isd
Name: Transferase/DNA
Title: Ternary complex of human DNA polymerase beta with an abasic site (thf): dapcpp mismatch
Structure: DNA polymerase beta. Chain: a. Engineered: yes. 5'-d(p Gp Tp Cp Gp G)-3'. Chain: d. Engineered: yes. 5'-d( Gp Cp Tp Gp Ap Tp Gp Cp Gp C)-3'. Chain: p. Engineered: yes.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: polb. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: chemically sytnthesized oligonucleotide. Other_details: chemically sytnthesized oligonucleotide
Resolution:
2.60Å     R-factor:   0.195     R-free:   0.262
Authors: W.A.Beard,D.D.Shock,V.K.Batra,L.C.Pedersen,S.H.Wilson
Date:
25-Aug-09     Release date:   15-Sep-09    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P06746  (DPOLB_HUMAN) -  DNA polymerase beta
Seq:
Struc:
335 a.a.
326 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.7.7.7  - DNA-directed Dna polymerase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Deoxynucleoside triphosphate
+ DNA(n)
= diphosphate
+ DNA(n+1)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   5 terms 
  Biological process     DNA biosynthetic process   12 terms 
  Biochemical function     catalytic activity     11 terms