PDBsum entry: 3ido

Hydrolase

PDB id: 3ido

Contents

Protein chains

158 a.a. *

Ligands

EPE ×2

Waters ×131

* Residue conservation analysis

PDB id:

3ido

Name:

Hydrolase

Title:

Crystal structure of protein tyrosine phosphatase from entamoeba histolytica with a phosphotyrosine crude mimic hepes molecule in the active site

Structure:

Protein tyrosine phosphatase. Chain: a, b. Engineered: yes

Source:

Entamoeba histolytica hm-1:imss. Organism_taxid: 294381. Gene: ehi_153650. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

2.20Å R-factor: 0.206 R-free: 0.254

Authors:

Seattle Structural Genomics Center For Infectious Disease (Ssgcid)

Key ref:

T.E.Edwards et al. Crystal structure of protein tyrosine phosphatase from entamoeba histolytica with a phosphotyrosine crude mimic hepes molecule in the active site. To be published,

Date:

21-Jul-09 Release date: 28-Jul-09

Protein chains

C4LSE7  (C4LSE7_ENTHI) -  Protein tyrosine phosphatase, putative

Seq: 157 a.a.

Struc: 158 a.a.

 Gene Ontology (GO) functional annotation 

• Biological process: protein amino acid dephosphorylation (1 term)
• Biochemical function: protein tyrosine phosphatase activity (1 term)