PDBsum entry: 3hqh

Ligase

PDB id

3hqh

Contents

			Protein chain

					134 a.a. *

			Ligands

					ALA-SER-ALA-ASP- SER-THR-THR-GLU- GLY

			Metals

					_ZN ×3

			Waters ×48

* Residue conservation analysis

PDB id:

3hqh

Links
- PDBe
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Name:

Ligase

Title:

Structures of spop-substrate complexes: insights into molecular architectures of btb-cul3 ubiquitin ligases: spopmathx-macroh2asbcpep1

Structure:

Speckle-type poz protein. Chain: a. Engineered: yes. Macroh2a. Chain: m. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: spop. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic peptide

Resolution:

2.30Å

R-factor:

0.238

R-free:

0.276

Authors:

M.Zhuang,B.A.Schulman

Key ref:

M.Zhuang et al. (2009). Structures of spop-Substrate complexes: insights into molecular architectures of btb-Cul3 ubiquitin ligases. Mol.Cell, 36,

Date:

06-Jun-09

Release date:

20-Oct-09

PROCHECK

	Headers

	References

Protein chain

O43791 (SPOP_HUMAN) - Speckle-type POZ protein

Seq: Struc:					374 a.a. 134 a.a.*

Key:

PfamA domain

Secondary structure

* PDB and UniProt seqs differ at 1 residue position (black cross)