PDBsum entry: 3hqc

Hydrolase

PDB id: 3hqc

Contents

Protein chain

140 a.a. *

Ligands

SO4 ×3

ACT ×2

GOL

Waters ×85

* Residue conservation analysis

PDB id:

3hqc

Name:

Hydrolase

Title:

Crystal structure of phosphotyrosine-binding domain from the tensin-like c1 domain-containing phosphatase (tenc1)

Structure:

Tensin-like c1 domain-containing phosphatase. Chain: a. Fragment: phosphotyrosine binding domain, ptb, residues 126 synonym: tenc1, c1 domain-containing phosphatase and tensin c1-ten, tensin-2. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: kiaa1075, tenc1, tns2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Modified pet26b

Resolution:

1.80Å R-factor: 0.214 R-free: 0.242

Authors:

P.Sampathkumar,R.Romero,S.Wasserman,J.Do,M.Dickey,K.Bain,T.G R.Klemke,S.Atwell,J.M.Sauder,S.K.Burley,New York Sgx Resear For Structural Genomics (Nysgxrc)

Key ref:

P.Sampathkumar et al. Crystal structure of phosphotyrosine-Binding domain from the human tensin-Like c1 domain-Containing phosphatase (tenc1). To be published,

Date:

05-Jun-09 Release date: 21-Jul-09

Protein chain

Q63HR2  (TENC1_HUMAN) -  Tensin-like C1 domain-containing phosphatase

Seq: 1409 a.a.

Struc: 140 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

 Gene Ontology (GO) functional annotation 

• Biochemical function: protein binding (1 term)