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PDBsum entry 3h78

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protein ligands Protein-protein interface(s) links
Transferase PDB id
3h78
Jmol
Contents
Protein chains
329 a.a. *
Ligands
BE2 ×3
Waters ×655
* Residue conservation analysis
PDB id:
3h78
Name: Transferase
Title: Crystal structure of pseudomonas aeruginosa pqsd c112a mutant in complex with anthranilic acid
Structure: Pqs biosynthetic enzyme. Chain: a, b. Engineered: yes. Mutation: yes
Source: Pseudomonas aeruginosa pao1. Organism_taxid: 208964. Strain: pa01 / 1c / prs 101 / lmg 12228. Atcc: 15692. Gene: pqsd, pa0999. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.70Å     R-factor:   0.152     R-free:   0.195
Authors: A.K.Bera,V.Atanasova,J.F.Parsons
Date:
24-Apr-09     Release date:   15-Sep-09    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P20582  (PQSD_PSEAE) -  PQB biosynthetic 3-oxoacyl-[acyl-carrier-protein] synthase III
Seq:
Struc:
337 a.a.
329 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Enzyme reactions 
   Enzyme class: E.C.2.3.1.180  - Beta-ketoacyl-[acyl-carrier-protein] synthase Iii.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Acetyl-CoA + malonyl-[acyl-carrier-protein] = acetoacetyl-[acyl-carrier- protein] + CoA + CO2
Acetyl-CoA
+ malonyl-[acyl-carrier-protein]
= acetoacetyl-[acyl-carrier- protein]
+ CoA
+ CO(2)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   1 term 
  Biological process     metabolic process   4 terms 
  Biochemical function     catalytic activity     6 terms